The RET tyrosine kinase signaling pathway is involved in the development of endocrine resistant ER+ breast cancer. However. we know little about how ER+ cells activate RET signaling and initiate an endocrine resistant phenotype. Here we show that both ER+ endocrine resistant and sensitive breast cancers have a functional RET tyrosine kinase signaling pathway. https://balboasurfandsstylers.shop/product-category/bag/