Isocyanide-based multicomponent reactions (IMCRs) allow the construction of relatively complex molecules through a one-pot synthesis. The combination of IMCRs in a consecutive or sequential fashion further extends the complexity of the molecules obtained. Herein. we report the efficient application of this approach to the synthesis of acylhydrazines bearing 1. https://www.roneverhart.com/MSI-Vector-GP68HX-12VH-012CA-16-FHD-Gaming-Laptop-Intel-Core-i9-12900HX-2-30-GHz-32GB-DDR5-1TB-SSD-GeForce-RTX-4080-W/